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Gentle Renewal Rx
Concentration
Tretinoin + Niacinamide 4% + Hyaluronic Acid
Purity
Provider reviewed
Unit
30g tube
Category
Prescription Skincare

Prescription Skincare

Gentle Renewal Rx

A retinoid your skin can keep up with.

Gentle Renewal Rx · Tretinoin + Niacinamide 4% + Hyaluronic Acid

Purchase type

Save 10% today and on every refill. Auto-renews at your selected cadence, pause or cancel anytime.

Cadence

Gentle Renewal Rx$134 billed monthly

Strength set by your provider. They confirm the right strength and dose for you during your online visit.

Coming Soon

Only available if prescribed after an online consultation with a licensed provider.

Free provider visitFree discreet shippingPause or cancel anytime

What's included

  • Medication and supplies
  • Provider visit and unlimited follow-ups
  • Free expedited shipping

Pause, change, or cancel anytime from your account.

About Gentle Renewal Rx

Most retinoid routines fail in the first month, when dryness sets in and people stop. This one pairs prescription tretinoin with niacinamide to support the skin barrier and hyaluronic acid to hold moisture, so the adjustment period is easier to ride out. Your provider sets the strength. Compounded by a US-licensed pharmacy.

How it works

Answer a few questions. Your provider reviews and prescribes if it fits. The pharmacy compounds and ships it; message your care team anytime.

What to expect

Gentler than tretinoin alone, but expect some early dryness. Tone and smoothness usually shift by week six to eight. Daily sunscreen keeps it on track.

  • Tretinoin paired with barrier support
  • Built to be tolerable enough to finish
  • Niacinamide for redness and pore appearance
  • Real pricing up front, discreet shipping

Evidence notes

Tretinoin is all-trans retinoic acid; niacinamide supports barrier function and hyaluronic acid draws water into the outer layer. Compounded by a US-licensed pharmacy.

Safety information

Not prescribed in pregnancy or breastfeeding, and it raises sun sensitivity. Your provider reviews your history first.

Frequently asked questions

Yes. They are combined in one compounded cream here. Niacinamide supports the skin barrier, which can make a retinoid easier to tolerate.

Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.